Volasertib decreased the clonogenic potential (Supplementary Fig. 7a), the viability (Supplementary Fig. 7b), induced cell death (Supplementary Fig. 7c), and caspase 2 activation (Supplementary Fig. 7d) of primary ccRCC cells (CC, MM, TF) while it had no effects on normal 15S cells (Supplementary Fig. 7b–d). The gene discussed is TF; the disease is nonpapillary renal cell carcinoma.