CLN3 and retinal degeneration: Similarly, a comparison of molecular and structural defects between CLN3 disease hiPSC-RPE cells and hiPSC-RPE derived from patients with CLN3-associated non-syndromic retinal degeneration would be instrumental in further elucidating the role of RPE dysfunction in instigating photoreceptor degeneration in CLN3 disease versus non-syndromic CLN3-associated retinal degeneration.