Further, significant negative correlations were found in mice treated with the curative dose of BZN between IL-17A and both parasitemia and cardiac parasite burden (r = -0.826, P-value Spearman 0.013; r = -0.86, P < 0.0001 respectively) (Fig. 4B and C, respectively), as well as between the cytokine IL-22 and both parasitemia and cardiac parasite burden (r = -0.812, P-value Spearman 0.010; r = -0.764, P < 0.0001 respectively) (Fig. 4D and E, respectively). Here, IL17A is linked to parasitic infectious disease.