The top 20 DMRs remained significant following removal of DS newborns with high erythroblasts (N = 34) or removal of GATA1 mutation-positive individuals (N = 30), and in ethnicity-stratified analyses with the exception of CCDC17, ANAPC2, and MIR1224, which were not detected in non-Latino whites. Here, ANAPC2 is linked to Dravet syndrome.