Neither removal of DS newborns with GATA1 mutations (N = 30) nor those with high erythroblasts (N = 34) affected EWAS results substantially, and ethnicity-stratified analyses showed similar results, with 622/652 (95.4%) epigenome-wide significant CpGs showing the same direction of effect in both Latinos and non-Latino whites (Supplementary Data 2). Here, GATA1 is linked to Dravet syndrome.