CD4 and Dravet syndrome: This confirmed several of the previously reported differences in neonatal blood cell proportions in DS compared with non-DS fetuses and newborns8,20 (Fig. 2a and Supplementary Fig. 4a), with similar patterns in Latino and non-Latino white newborns (Supplementary Fig. 5), including higher proportions of erythroblasts (nucleated red blood cells (nRBCs)) (P = 4.45 × 10−65) and lower proportions of B lymphocytes (P = 3.48 × 10−28) and T lymphocytes (CD4+ T lymphocytes) (P = 2.26 × 10−53) (Supplementary Fig. 4a and Supplementary Table 2)8,20.