In addition, we identified 59 DMRs associated with GATA1 mutations in DS neonates (Supplementary Data 6); the most significant region encompassed the noncoding RNA VTRNA2-1 (P = 1.71 × 10−20), with reduced DNA methylation (mean Δβ-value = −0.115) in GATA1 mutation-positive DS newborns versus wild-type DS newborns. The gene discussed is GATA1; the disease is Dravet syndrome.