MAPT and Alzheimer disease: In contrast, within subjects with relatively low neocortical tau levels, higher [18F]flortaucipir BPND was associated with higher [11C]UCB-J BPND across ROIs (AD subject 6–7: r = 0.47, p = 0.02, and r = 0.57, p = 0.004, respectively) (Fig. 2b).