miR-501-3p and WDR82 expression in tissues were assessed and we found that LC tissues had higher miR-501-3p expression and lower WDR82 expression versus adjacent normal tissues (Fig. 1b, c), and the Pearson test revealed that there existed a negative relationship between expression of miR-501-3p and WDR82 (Fig. 1d). The gene discussed is WDR82; the disease is laryngotracheoesophageal cleft.