Moreover, an additional increase was observed following incubation with SLE NET compared to those incubated with healthy NET, which is in agreement with the reports by Ribon et al. [39], who showed a higher upregulated CD11b expression on neutrophils following exposure to higher levels of purified chromatin, or the study by Lindau et al. [40], who demonstrated a clear dose-dependent effect for nucleosomes on the upregulation of CD11b expression in neutrophils. The gene discussed is ITGAM; the disease is systemic lupus erythematosus.