MAP1LC3A and type 1 diabetes mellitus: Zhan et al. reported that hyperglycaemia inhibited the expression of PINK1, punctate LC3 (microtubule-associated protein 1A/1B-light chain 3), and mitochondrial profusion protein Mfn2, but increased the expression of mitochondrial fission protein Drp1 and Fis1 in renal proximal tubular cells under high-glucose conditions and in streptozotocin (STZ)-induced type 1 diabetic mice [63].