The aims of this study were to evaluate the accuracy of the IP message for hemoglobin defects (“Hb defect”) in identifying Cambodian women with a genetic hemoglobinopathy by comparing these flags to definitive testing performed through hemoglobin electrophoresis and to determine which combination of CBC biomarkers can best predict the presence of a genetic hemoglobinopathy. Here, GSTM1 is linked to hemoglobinopathy.