The various mechanisms of their anticancer action have been widely explored [22,23,24,25,26,27,28], including inhibition of carbonic anhydrase, PI3K/AKT/mTOR signaling pathway, microtubule polymerization, monocarboxylate transporters, hypoxia-inducible factor-1, acting on apoptosis proteins, inhibiting tumor multidrug resistance, and regulating ROS. Here, AKT1 is linked to neoplasm.