However, an increasing number of atypical cases have been diagnosed by FOXP3 gene sequencing, indicating various manifestations of IPEX syndrome.[6,7] IPEX syndrome patients who present with atypical symptoms have often been misdiagnosed before the correct diagnosis, or received the information late in life. The gene discussed is FOXP3; the disease is immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.