We reconfirmed that the patient had HAE-C1-INH through laboratory examinations (C1-INH function level: < 25.0%), although serum C4 and CH50 levels were elevated to the normal values by the previously prescribed attenuated androgens (C4: 22 mg/dl, CH50: 54 U/ml, C3: 97 mg/dl). Here, C4A is linked to hereditary angioedema.