Pearson’s correlation analysis in the present patients with GBM demonstrated that the P/C ratio of CD44 was significantly more correlated with PFST on Bev therapy than mRNA expression of CD44 in the tumor periphery, whereas mRNA expression of VEGF in the tumor periphery showed significantly a much better correlation with PFST than the P/C ratio of VEGF (Figure S2).These results suggest that the present evaluation of the degree of CD44 and VEGF expression is more appropriate than other assessments. This evidence concerns the gene CD44 and glioblastoma.