In solid tumors, SGK1 is often upregulated in most of the cancer, such as adrenocortical adenomas (26), breast cancer (14), endometrial cancer (30), gastric cancer (GC) (15), lung cancer (16, 17, 31), medulloblastoma (32), oral squamous cell carcinoma (OSCC) (33), ovarian cancer (34), prostate carcinoma (20, 35), renal clear cell carcinoma (32), and rhabdomyosarcoma (36). This evidence concerns the gene SGK1 and cancer.