SGK1 and ovarian carcinoma: In ovarian carcinoma, in vitro assays showed that in glucocorticoid receptor (GR)-positive HeyA8 and SKOV3 cells, dexamethasone (100 nM) treatment upregulated the pro-survival genes SGK1, and MKP1/DUSP1 and inhibited carboplatin/gemcitabine-induced cell death (93).