COL1A1 and nonpapillary renal cell carcinoma: As shown in Figures 7A–N, the expression of SFTPB, THBS2, SCGB1A1, NKX2-1, COL11A1, DCN, and COL1A1 increased significantly in ccRCC tissues compared with adjacent normal kidney tissues (P < 0.05, P < 0.01) and the expression of SFTPC, FBLN1,LUM, and COL6A3 increased in ccRCC tissues, while the levels of miR-328, miR-502, and miR-504 greatly decreased in ccRCC tissues (P < 0.01).