We found that inhibition of the Menin/Kmt2a interaction decreased colony formation (Fig. 5A) and cell growth (Supplementary Fig. S4A) in methylcellulose in MN1-driven AML cells, but not in control cells driven by retroviral overexpression of Hoxa9 and Meis1. The gene discussed is HOXA9; the disease is acute myeloid leukemia.