Several studies also suggest a genetic and epigenetic association between TNXB and psychiatric disorders such as schizophrenia42,43 or anorexia nervosa44,45 and, strikingly, hypomethylation of a CpG site in intron 6 of TNXB has already been associated with panic disorder in an EWAS12. The gene discussed is TNXB; the disease is psychiatric disorder.