ZDHHC15 and central nervous system cancer: We first compared ZDHHC15 expression in 60 glioma tissues, including pilocytic astrocytoma (PA, grade I; n = 6), oligodendrocytoma (OL, grade II, n = 18), anaplastic astrocytoma (AA, grade III; n = 15), and GBM (grade IV; n = 21), and eight normal brain tissue samples (Fig. 3a).