She underwent Invitae Multi-Cancer panel genetic testing (Supplemental Table 1) that detected heterozygous mutations in BRCA1-associated protein 1 (BAP1), MutS Homolog 6 (MSH6) and ATP-dependent DNA helicase Q1 (RECQL4) genes, all noted to be “pathogenic” or “likely pathogenic.” The gene discussed is MSH6; the disease is cancer.