ANGPT2 and acute kidney injury: Omitting patients from the analysis whose AKI resolved by 48 or 72 h, the plasma levels of angiopoietin-2 remained significantly lower in patients without any AKI within the four study days compared to patients with unresolved AKI at 48 (6395 pg/ml, IQR 2706–11,985 pg/ml) or 72 (6395 pg/ml, IQR 3000–11,514 pg/ml) hours after enrollment (Additional file 3: Fig. S3b).