ANGPT2 and acute kidney injury: Furthermore, the plasma levels of angiopoietin-2 were significantly lower in those who had resolution of AKI in the subsequent 48 or 72 h compared to patients who had persistent AKI at 48 h (4221 pg/ml, IQR 1854–5966 pg/ml vs. 6395 pg/ml, IQR 2706–11,985 pg/ml, p = 0.027) or 72 h (3805 pg/ml, IQR 1744–6475 pg/ml vs. 6395 pg/ml, IQR 3000–11,514 pg/ml, p = 0.008) after enrollment (Additional file 3: Fig. S3c).