The results demonstrated that cyclin D1, N-cadherin were upregulated, and p21, occludin were downregulated in CCDC183-AS1 overexpression HCC cells, while the expression levels of these indicators were reversed when CCDC183-AS1 was attenuated (Fig. 6f and Supplementary Fig. 6G). This evidence concerns the gene CCDC183 and hepatocellular carcinoma.