PRKCA and posterior cortical atrophy: However, the interactions of excessive alcohol intake and three SNPs (rs13107662 [CAMK2D, p = 6.2 × 10−6], rs9907521 [PRKCA,p = 7.1 × 10−5], and rs11925452 [ROBO1, p = 8.2 × 10−4]) were significantly associated with PCa aggressiveness.