Pathway analysis for the genes associated with the alteration in H3K27ac in HCV infected and cured liver samples also identified cancer and inflammation-related pathways, including TNFa signaling, inflammatory response, G2M checkpoint, epithelial–mesenchymal transition, phosphoinositide 3-kinase, Akt, and mammalian target of rapamycin [mTOR) [8]. Here, MTOR is linked to cancer.