MTOR and cancer: In cell culture, we showed that integration of the changes in H3K9Ac and gene expression alteration revealed that the altered genes are related to cytoskeleton remodeling (TGF, WNT), transport clathrin-coated vesicle cycle, cell cycle, development, immune response, B-Raf, NGF, mTOR/MAPK, lipid metabolism, endocytosis and membrane trafficking and epigenetic modifiers, among other cancer-related pathways [7].