AKT3 and posterior cortical atrophy: After transfection of PCa cells with an AKT3 expression vector, the AKT3 protein level of LNCaP cells were 13.6-fold (Figure S3A), 22Rv1 cells 16.8-fold (Figure S3B), DU145 cells 7.4-fold (Figure S3C) and PC3 cells 11.6-fold (Figure S3D) increased.