VWF and COVID-19: In agreement with these reports, hyperglycemia has been shown to downregulate miR-24 expression in plasma and tissue and knocking miR-24 down in mice leads to increased expression and secretion of von Willebrand factor in endothelial cells, accompanied by a significantly enhanced platelet tethering [79], thereby suggesting a pathophysiologic role for this miRNA in the thromboembolic complications described in COVID-19 [49,80,81,82].