A significant positive correlation was found between serum GP73 and TBA (r = 0.540, p < 0.001) in patients with cirrhosis, higher than that in non-cirrhotic CLD (r = 0.318, p < 0.001) and HCC patients (r = 0.353, p < 0.001) (Figure 1A–C). Here, GOLM1 is linked to congenital secretory chloride diarrhea 1.