In addition, the direct estimates of depression reduction in the league table also revealed the significant superiority of BWLT against ALT (SMD = -0.55, 95%CI = -1.09 to -0.01) and NLT (SMD = 0.77, 95% CIs = -1.42 to -0.12) (see Table 2C). The gene discussed is GPT; the disease is depressive disorder.