On the other hand, GLUT1 and GLUT3 are considered as potentially useful markers for the differentiation of melanoma from nevi, as patients with GLUT1- and GLUT3-positive melanomas had significantly lower survival rate than those who lacked GLUT1 and GLUT3 expression in their melanomas [13, 56, 57]. This evidence concerns the gene SLC2A3 and melanoma.