IDH-mut oligodendrogliomas had the longest median OS (16.6 years), followed by IDH-mut astrocytomas (10.0 years) and IDH1-R132H-nm gliomas (3.1 years; p < 0.001 for all; Fig. 1a, b). This evidence concerns the gene IDH1 and astrocytoma (excluding glioblastoma).