In addition, other case reports suggested the association of a LTP sensitization and food-dependent exercise-induced anaphylaxis (FDEIA) in a patient from Poland after eating several, also LTP-containing, foods [46] and demonstrated the presence of IgE to apple LTP in a German patient with food allergy to apple but without sensitization to Bet v 1-like proteins, storage proteins, or profilin [29]. Here, IGHE is linked to allergic disease.