A total of 129 serum samples collected from COVID-19 patients admitted to Wuhan Huoshenshan Hospital were tested with SARS-CoV-2 specific IgG and IgM Ab detection kits using the indirect immunity method, produced by manufacturer A. Before testing, samples were heat-inactivated in water bath at 56°C for 30 min, 56°C for 45 min, 56°C for 60 min, 60°C for 30 min, or 65°C for 30 min. Here, CD40LG is linked to COVID-19.