CHCHD2 was not only recorded in hepatocellular carcinoma (HCC) cells but also tissues whereCHCHD2 protein level was remarkably relatable with poor differentiation, lymph node metastasis, local tissue invasion, angiogenesis, and poor prognosis in patients (Yao et al., 2019). The gene discussed is CHCHD2; the disease is hepatocellular carcinoma.