PRKN and Parkinson disease: Interestingly, Miro1/RhoT1 is a target of the PINK1/Parkin pathway for mitochondrial quality control (Wang et al., 2011; Shlevkov et al., 2016), and defective proteostasis of Miro1 has been observed in human-induced pluripotent stem cell (hIPSC) lines derived from PD patients (Hsieh et al., 2019).