A recent report demonstrated that this resistance could be mediated by the upregulation of an apoptosis inhibitory Fas-interacting tyrosine phosphatase (PTPN13, also known as FAP-1) 22, emphasizing the potential of PTPN13 as an intervention target for promoting (myo)fibroblast apoptosis during the development of IPF. The gene discussed is PTPN13; the disease is idiopathic pulmonary fibrosis.