SIRT1 and liver dysplastic nodule: Overexpression of long intergenic ncRNA (lincRNA) 1700020I14Rik has been verified to interact with miR-34a-5p through direct targeting as well as an argonaute-2 dependent manner to inhibit cell proliferation and fibrosis through the SIRT1/hypoxia-inducible factor-1α (HIF-1α) signaling pathway during the progression of DN (74).