Similarly, some authors demonstrated a reduction of Bcl-2 gene or protein expression in endothelial cells (Morbidelli et al., 2005; Kang et al., 2011; Li et al., 2019; Tang et al., 2019), human osteoblastic cells (Nakamura et al., 2003), and carcinoma cells (Kossmehl et al., 2003). Here, BCL2 is linked to carcinoma.