HBS1L and Tangier disease: The rs9399136[C] variant in the intergenic HBS1L/MYB region is the only variant to associate with both IDA (OR = 0.84 [0.80–0.89], P = 4.7 × 10−11) and iron overload (OR = 1.13 [1.07–1.20], P = 1.4 × 10−5).