Rare loss-of-function mutations in SLC11A2 (solute carrier family 11 member 2 encoding DMT1, divalent metal transporter 1) have been associated with a microcytic anemia with iron overload under the recessive mode of inheritance58–60 demonstrating a role of DMT1 in both iron absorption and recycling. This evidence concerns the gene SLC11A2 and microcytic anemia.