TMPRSS6 and hemochromatosis type 1: Taking all 62 × 11 = 682 tests into account using Bonferroni correction, the TMPRSS6 p.Val749Ala variant (rs855791[A]) associates with less risk of hemochromatosis (Ncases = 719, Ncontrols = 497,001; OR = 0.80 [0.72–0.89], P = 6.1 × 10−5).