For breast cancer GWAS35, enriched in epithelial and cancer biosamples (Extended Data Fig. 9c), the highly localized rs17356907 genetic signal (P = 10−39, rank no. 12) localized precisely in a narrow epithelial and cancer enhancer nearest to USP44 but linked instead to NTN4, which is implicated in tumorigenesis and angiogenesis (Extended Data Fig. 9d). This evidence concerns the gene USP44 and cancer.