Consequently, IgA and pIgR colocalized at tumour beds within cytokeratin (PCK)-positive tumour islets in 273 HGSOCs we analysed (Fig. 1e), and IgA–pIgR colocalization—but not pIgR-overexpression alone or stromal IgA—is associated with improved survival (Fig. 1f, Extended Data Fig. 2f, g). This evidence concerns the gene PIGR and neoplasm.