Among G6PD variants detected in this study, Kaiping, Union, Valladolid, and Coimbra were classified as Class II variants (causing severe deficiency) while Canton, Mahidol, Viangchan, Aures, and Gaohe were classified as Class III variants (causing moderate-to-mild deficiency) according to the World Health Organization’s classification on the level of enzyme activity27 (Table 2). Here, G6PD is linked to hyperinsulinemic hypoglycemia, familial, 4.