On the other hand, the reduction in the number of Ki67-positive cells (Fig. 3G,J) and decrease in CD31-positive tumour microvessels (Fig. 3H,K) in the LFD/AdipoRon group were more remarkable than those in the HFD/AdipoRon group, suggesting the possibility that suppression of angiogenesis was partially responsible for the growth inhibition and necrosis. The gene discussed is MKI67; the disease is neoplasm.