Similar pH profiles were observed for the aminopeptidase activity measured in the malaria cytosolic extract using the substrate H-Ala-NHMec, that is preferentially cleaved by PfM1AAP compared to PfM17LAP, and with H-Arg-NHMec, which is exclusively cleaved by PfM1AAP6,7 (Fig. 7B). This evidence concerns the gene CPQ and malaria.