Logistic regression modelling revealed that serum MMP7 remained independently associated with clinically significant fibrosis (LSM ≥ 8.2 kPa) after accounting for potential confounding factors (patient age, gender, BMI and diabetes (adjusted Odds Ratio (aOR) 9.65, 95% CI 3.09–30.13) (Table 2). This evidence concerns the gene MMP7 and diabetes mellitus.