Finally, a previous study with NSC207895 proposed that the effects of the inhibitor were mediated through off-target effects on the genes EDIL3, FLOT1, HEG1, UTRN, KIF20A, IDH1, and GPSM2 in studies of Ewing sarcoma and osteosarcoma cell lines34. The gene discussed is HEG1; the disease is Ewing sarcoma.