Based on the above results of univariate analysis, we determined 19 risk factors including severity evaluation at admission, gender, age, BMI, temperature, cough, shortness of breath, hemoptysis, hypertension, diabetes, secondary bacterial infection, lung consolidation, lymphocyte count, CK, NLR, ALT, AST, LDH, and CRP as inputs to the model to evaluate whether COVID-19 patients would develop ARDS. This evidence concerns the gene CRP and COVID-19.