LDHA and neoplasm: For instance, the forced expression of miR-200a/miR-200b in MCF10 mammary cells induced an enhanced epithelial program, aldehyde dehydrogenase (ALDH) activity, mammosphere growth and ability to form branched tubuloalveolar structures while promoting orthotopic tumor growth and lung colonization in vivo, suggesting that miR-200 family members may promote traits of highly proliferative breast luminal progenitor cells7.