Two further cases were diagnosed as PDAC upon biopsy; conventional cytology was positive and NGS revealed pathogenic variants of KRAS and TP53. In two other cases, PDAC was also diagnosed in biopsy; in both cases, conventional cytology was negative and NGS revealed a pathogenic variant of KRAS, at least indicative of mucinous neoplasm. Here, TP53 is linked to mucinous neoplasm.