In detail, 10/15 IPMN could have been diagnosed as mucinous neoplasms by the presence of KRAS and/or GNAS variant, whereas both non-mucinous lesions (one ITPN and one SCN) did not show variants either in KRAS or in GNAS. In addition, diagnosis of IPMN instead of a generic diagnosis of “mucinous neoplasms” could have been made in 5/15 IPMN cases (33.3%), in which a pathogenic GNAS variant was found. Here, GNAS is linked to severe congenital neutropenia.