SH2B3 and coronary artery disorder: For example, at the well-studied SH2B3-ATXN2 region26,35, HyPrColoc detected two cholesterol measures (LDL, HDL), two blood pressure measures (SBP, DBP) and rheumatoid arthritis (RA) colocalizing with CHD at the previously reported CHD-associated SNP26 rs7137828 (PPFC = 0.909 of which 76.8% is explained by the variant rs7137828; Fig. 8).