Also, although the hepatic and systemic action of LCN13 have been studied to some degree already, a potential role of LCN13 for pancreatic islet function has not been investigated thus far, but given the critical importance of islet function for glucose control and the pathogenesis of diabetes, it is clearly needed to establish a comprehensive picture of LCN13’s therapeutic capacities. This evidence concerns the gene OBP2A and diabetes mellitus.