In our study groups, the distribution by sex (50.7% women vs. 49.3% men) and associated significant comorbidities (mainly cardiovascular disease, the most frequent being heart failure and arterial hypertension) was approximately equal; 86.6% of patients had echocardiographically confirmed RV dysfunction or elevated serum troponin/BNP levels. This evidence concerns the gene NPPB and Hypertension.